Drug class
Aliases:
Topic aliases are alternate phrasings for a particular topic.
ACE-I
Angiotensin converting enzyme inhibitors
Angiotensin converting enzyme inhibitor
A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin angiotensin-system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
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Some concern exists around the occurrence of hypotension following the use of leukocyte reduction-filters for blood products in patients taking ACE inhibitors.
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Although this phenomenon is also thought the occur in patients not taking ACE inhibtors.
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Although this phenomenon is also thought the occur in patients not taking ACE inhibtors.
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