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A nucleoside that is composed of adenine and d-ribose. Adenosine itself is a neurotransmitter.
www.nlm.nih.gov/cgi/mesh/...
Adenosine is also utilised therapeutically for its action as a AV nodal blocker in the management of SVT.

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For reversion of supraventricular tachycardia-svt
1. first dose at 100mcg/kg
2. after 2min the second dose is 200mcg/kg
3. after 2min the third dose is 300mcg/kg

Maximum single dose for neonate is 300mcg/kg

Maximum single dose for child > 1mth is 500mcg/kg

Max total dose 12mg

#apls

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When administering to revert SVT, delivery as a concentrated bolus is an imperative. Connect a 3-way tap to a proximal peripheral vein, connect adenosine dose to one port, 20ml normal saline to the other. Immediately after administering adenosine rotate 3-way tap and flush with normal saline.

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1
Adenosine can work when given through an intraosseus cannula with an adequate flush.

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