An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING-ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE-INHIBITORS or with ANGIOTENSIN II-TYPE-1-RECEPTOR-BLOCKERS.
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Nov 26, 2012