Singh-Vaughn-Williams classification is based upon mechanism of action
Class 1-Antiarrhythmic agents interfere with the sodium (Na+) channel.
Class 2-Antiarrhythmic agents are anti-sympathetic nervous system agents. Most agents in this class are beta blockers.
Class 3-Antiarrhythmic agents affect potassium (K+) efflux.
Class 4-Antiarrhythmic agents affect calcium channels and the AV node.
Class 5-Antiarrhythmic agents work by other or unknown mechanisms.
Class 1-Antiarrhythmic agents interfere with the sodium (Na+) channel.
Class 2-Antiarrhythmic agents are anti-sympathetic nervous system agents. Most agents in this class are beta blockers.
Class 3-Antiarrhythmic agents affect potassium (K+) efflux.
Class 4-Antiarrhythmic agents affect calcium channels and the AV node.
Class 5-Antiarrhythmic agents work by other or unknown mechanisms.
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Dec 01, 2012