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Drug
 
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ACE inhibitor

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Consider in postop paediatric cardiac patients likely to have long term myocardial dysfunction (eg single ventricles)

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0.1mg/kg (Max 2.5-5mg) 8/24 titrated carefully up to max 2mg/kg (adult 50mg ) 8/24.

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In infants, administering with continuous feeds rather than intermittent feeds may smooth out haemodynamic response

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Consider alternative antihypertensives ( calcium channel blockers) in patients on nephrotoxic drugs (eg transplant patients on cyclosporin)

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Watch renal function as increasing dose

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Aspen pharma solution

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