Patient (condition)
 
Aliases:
End stage kidney disease (ESKD)
End-stage kidney disease

Topic aliases are alternate phrasings for a particular topic.


Electrolytes taken immediately post dialysis are unreliable as it will take time for electrolytes to reequilibrate

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Myocardial ischaemia might imply that the patient is volume overloaded. Organise urgent haemofiltration to reduce intravascular volume if this is thought to be the case.

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Intra-arterial blood pressure monitoring may aid in achieving tight volume control

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Ask the patient what their dry weight is and what their current weight is. A >2kg difference suggests patient may already be at upper limit of intravascular volume. Be cautious with additional volume.

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Dialysis patients often tolerate lower blood pressures. Clinical signs of brain and myocardial perfusion may be used to determine adequate mean arterial pressures.

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If excessive non-surgical bleeding encountered and is thought that it may be due to hyperuricaemic platelet dysfunction, consider use of desmopressin to improve platelet aggregation #ref

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Avoid NSAIDs if the patient still makes urine or is a renal transplant recipient to avoid further renal damage. Daily urine output increases the patient's daily fluid restriction limit and improves their quality of life.

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Expect prolonged action of aminosteroid muscle relaxants (rocuronium, vecuronium) as they are renally excreted. Benzylisoquinoliniums that do not rely on renal excretion such as atracurium may be a better alternative.

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1
Platelet adhesion and aggregation is decreased, probably as a result of inadequate vascular endothelial release of a von Willebrand factor/factor VIII complex. refl.in/85

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Nov 04, 2011
Uremic thrombocytopathy is another possible cause of platelet dysfunction that may respond to dialysis.
This paper looking at platelet function in patients with familial azotemia suggests urea is not the cause of platelet dysfunction. refl.in/lq