Aliases:
Arixtra
Fondiparinux

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Unlike direct factor-Xa-inhibitors, it mediates its effects indirectly through antithrombin III, but unlike heparin, it is selective for factor Xa.
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"The antithrombotic activity of fondaparinux sodium is the result of antithrombin III (ATIII)-mediated selective inhibition of Factor Xa. By selectively binding to ATIII, fondaparinux sodium potentiates (about 300 times) the innate neutralization of Factor Xa by ATIII. Neutralization of Factor Xa interrupts the blood coagulation cascade and thus inhibits thrombin formation and thrombus development."
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