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A 29-amino acid pancreatic peptide derived from proglucagon which is also the precursor of intestinal GLUCAGON-LIKE PEPTIDES. Glucagon is secreted by PANCREATIC ALPHA CELLS and plays an important role in regulation of BLOOD GLUCOSE concentration, ketone metabolism, and several other biochemical and physiological processes. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1511)

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Dose in beta blocker-overdose 50mcg/kg IV loading dose, infusion in adult 1-15mg/hr #ref

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In beta-blocker overdose: 0.1mg/kg IV stat, then 0.3-2 mcg/kg/min.

refl.in/drugdoses

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Chronotrope and inotrope that also improves AV conduction. Bypasses b-adrenergic receptor site. #ref

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