Guilliane Barre Syndrome
Patient (condition)
 
Aliases:
Guilian Bare syndrome

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Acute demyelinating polyneuropathy characterised by a an ascending sensory, motor, and autonomic deficit. Extent of recovery after acute illness is variable.

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Sep 06, 2011
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An acute inflammatory autoimmune neuritis caused by T cell- mediated cellular immune response directed towards peripheral myelin. Demyelination occurs in peripheral nerves and nerve roots. The process is often preceded by a viral or bacterial infection, surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations include progressive weakness, loss of sensation, and loss of deep tendon reflexes. Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et al., Principles of Neurology, 6th ed, pp1312-1314)

www.nlm.nih.gov/cgi/mesh/...

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Jan 24, 2013
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Consider drawing up vasopressors prior to induction to manage consequences of autonomic dysfunction.

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Sep 05, 2011
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May have autonomic dysfunction and impaired response to hypotension from anaesthesia/IPPV/postural change.

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Sep 05, 2011
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At risk of hyperkalemia with suxamethonium from proliferated extrajunctional neuromuscular junction NMJ receptors. refl.in/iy refl.in/iz

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Sep 24, 2011
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Non-depolarising muscle relaxants NMDR may not be needed. To be used with caution.

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May 18, 2011
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Patient may require postop ventilation. Take prexisting respiratory muscle involvement and nature of procedure into account.

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Sep 10, 2011
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