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Consult a haematologist regarding perioperative management

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Maintain factor levels at 50-100% at time of surgery for 2 - 7 days #oha

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Avoid administering blood products, where possible, to delay formation of antibodies/inhibitors in their lifetime

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Avoid drugs that affect coagulation and platelet function (NSAIDS, heparin, antiplatelet agents)

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Avoid intramuscular injections. These may cause haematomas.

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For mild disease or surgery at low risk of bleeding can use DDAVP 0.3mcg/kg in 30ml NSaline over 30min, and tranexamic acid. #review

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