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Reanalysis of 2004 SAFE study trial data in 2006 suggested that the outcomes of resuscitation with albumin and saline are similar irrespective of patients' baseline serum albumin concentration. refl.in/dw

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Serum albumin concentration is an independent predictor of mortality risk. Literature review/cohort study 1997 estimated increase in the odds of death ranges from 24% to 56% for each 2.5 g/l decrement in serum albumin. After adjusting for other known risk factors & preexisting illnesses, there appears to be direct protective effect of the albumin molecule. refl.in/dv

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