Hypophosphatasia
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Heterogenous genetic variation in activity of alkaline phosphatase resulting in a syndrome of osteopenia and recurrent bone fractures resembling ricketts. refl.in/ib

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Anemia may be present, possibly related to boney encroachment of bone marrow.

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Variable respiratory compromise may be present from chest wall abnormalities related to rib fractures.

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Ensure adequate perioperative hydration to minimise the risk of developing hypercalcuric renal stones. refl.in/ib

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Premature loss of deciduous and permanent teeth is common. Document condition of existing teeth.

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