Hypoxia is present when the processs of oxidative phosphorylation stops due to inadequate utilisation of oxygen.
This can be roughly categorised into causes of cellular hypoxia and causes of hypoxaemia.
A. Cellular Hypoxia
1. Circulatory hypoxia (insufficient tissue perfusion)
2. Anaemic hypoxia (insufficient Hb carrying capacity)
3. Histotoxic hypoxia (inability to utilise available oxygen - eg cyanide toxicity )
4. Hypoxaemic hypoxia ( sub maximal oxygenation of blood )
B. Hypoxaemia
1. Decreased minute ventilation
2. Decreased FiO2
3. Alveolar diffusion deficit
4. Shunt
5. V/Q Mismatch
This can be roughly categorised into causes of cellular hypoxia and causes of hypoxaemia.
A. Cellular Hypoxia
1. Circulatory hypoxia (insufficient tissue perfusion)
2. Anaemic hypoxia (insufficient Hb carrying capacity)
3. Histotoxic hypoxia (inability to utilise available oxygen - eg cyanide toxicity )
4. Hypoxaemic hypoxia ( sub maximal oxygenation of blood )
B. Hypoxaemia
1. Decreased minute ventilation
2. Decreased FiO2
3. Alveolar diffusion deficit
4. Shunt
5. V/Q Mismatch
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Dec 24, 2012