Patient (condition)
 
Aliases:
Prolonged QT Syndrome
LQTS
Qtc Prolongation

Topic aliases are alternate phrasings for a particular topic.


"Long QT syndrome is a congenital disorder characterized by a prolongation of the QT interval on electrocardiograms (ECGs) and a propensity to ventricular tachyarrhythmias, which may lead to syncope, cardiac arrest, or sudden death."
emedicine.medscape.com/ar...

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A condition that is characterized by episodes of fainting ( SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO WARD-SYNDROME and JERVELL LANGE-NIELSEN-SYNDROME.
www.nlm.nih.gov/cgi/mesh/...

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Treatment principles for cardiac arrythmias in the setting of QT prolongation.

Treat cause,
Cardioversion,
Overdrive Pacing,
Isoprenaline,
Magnesium 30mg/kg (or 1-2g) over 2-3 minutes as a bolus,
Phenytoin 1g,
Mexilitine or lignocaine,
Avoid class Ia, Ic and III antiarrythmics #ref

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Avoid tachycardia which may precipitate arrhythmias

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At increased risk of torsade de pointe. Do not use amiodarone if this occurs. #ref #improve refl.in/4b

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Avoid drugs that prolong the QT interval (eg haloperidol, droperidol, amiodarone, amitryptiline, halothane, clarithromycin) refl.in/4b

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Consider avoiding Ondasetron as it may prolong the QT interval refl.in/iw

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