Patient (condition)
 
Aliases:
NMS

Topic aliases are alternate phrasings for a particular topic.


Precipitant drugs include antipsychotics ( haloperidol, droperidol, clozapine, respiridone)

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Triad of signs:
Hyperthermia (98%);
lead pipe muscle rigidity (97%);
CNS disturbance (97%).
Others include tachycardia, hyper/hypotension, tachypnoea, diaphoresis. refl.in/nms

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Management is ABCD, cease precipitant drug. Muscle relaxation with NDMR or Dantrolene will help with ventilation. Send to ICU for ventilatory and metabolic/haemodynamic support. refl.in/nms

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Avoid anticholinergics as they may exacerbate tachycardia. refl.in/nms

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