Osteogenesis Imperfecta
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Anaesthetic considerations are risk of fractures during positioning or transfer, difficult laryngoscopy, dental damage, tendency to bleed due to platelet dysfunction and fragile capillaries, and restrictive lung disease in patients those patients with chest wall abnormalities.
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COLLAGEN DISEASES characterized by brittle, osteoporotic, and easily fractured bones. It may also present with blue sclerae, loose joints, and imperfect dentin formation. Most types are autosomal dominant and are associated with mutations in COLLAGEN TYPE I.
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