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Rabies immunoglobulin (RIG) should be given for all category III exposures, irrespective of the interval between exposure and beginning of treatment. Two kinds of rabies antibody preparations may be used: human rabies immunoglobulin (HRIG) and equine rabies immunoglobulin (ERIG). A skin test must be performed prior to the administration of ERIG. As much as possible of the recommended dose (20 IU/kg of body weight of HRIG or 40 IU/kg of body weight of ERIG) should be infiltrated around the wounds if anatomically feasible. The remainder should be administered intramuscularly (into gluteal region) in a single dose and followed by a complete course of vaccine.
www.who.int/rabies/human/...

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Jul 10, 2012
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