Sickle Cell Disease
Patient (condition)
 
Aliases:
Sickle cell anaemia

Topic aliases are alternate phrasings for a particular topic.


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A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.
www.nlm.nih.gov/cgi/mesh/...

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Aug 19, 2012
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Consider investigating organ dysfunction secondary to haemosiderosis associated with repeated transfusions. (Heart, liver, pancreas)

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May 21, 2011
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Cross-matching time may be prolonged in those who have previously received multiple transfusions.

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May 21, 2011
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Limb torniquet use has been shown to be safe as long as oxygenation and acid-base status are stable. refl.in/5m refl.in/5n

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May 21, 2011
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Avoid factors that would precipitate sickling, namely, hypoxia, hypercarbia, acidosis, hypothermia and low flow states. www.frca.co.uk/article.as...

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Aug 18, 2012
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Consider regional anaesthesia. Sympathetic block will cause vasodilatation leading to increased peripheral perfusion. refl.in/5g

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May be on chronic pain medications which may impact peri-operative analgesia

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May 21, 2011
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If tranfusing perioperatively, try to avoid acutely raising the haemaglobin by more than 3g/dL to avoid precipitating a crisis.

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