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IV Infusion: 0.25-10 microgram/kg/min;
maximum of 6 microgram/kg/min for neonates
RCH Paediatric Pharmacopoeia - 13th edition 2002
maximum of 6 microgram/kg/min for neonates
RCH Paediatric Pharmacopoeia - 13th edition 2002
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Oct 27, 2012
If giving high doses for several days monitor blood cyanide, and maintain whole blood level at less than 1 mg/L or serum level at less than 80 microgram/L.
RCH Paediatric Pharmacopoeia - 13th edition 2002
RCH Paediatric Pharmacopoeia - 13th edition 2002
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Oct 27, 2012
Sign of cyanide toxicity is tachyphylaxis and high mixed venous pO2 (due to decreased oxygen utilisation - histotoxic tissue hypoxia)
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Dec 24, 2012