Naloxone is included in the preparation to discourage injection of buprenorphine. Naloxone is poorly absorbed sublingually and orally but if injected can reduce the agonist effects of buprenorphine and may precipitate unpleasant withdrawal symptoms in people who are opioid dependent. www.health.gov.au/interne...
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See management of acute pain in patients taking buprenorphine
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Suboxone product information www.suboxone.com/pdfs/Sub...
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