Patient (condition)
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CDC Case definition.
An illness with the following clinical manifestations:
Fever -- temperature greater than or equal to 38.9 C (102 F)
Rash -- diffuse macular erythroderma
Desquamation -- 1-2 weeks after onset of illness, particularly palms and soles
Hypotension -- systolic blood pressure less than or equal to 90 mm Hg for adults or less than fifth percentile by age for children <16 years of age; orthostatic drop in diastolic blood pressure greater than or equal to 15 mm Hg from lying to sitting, orthostatic syncope, or orthostatic dizziness
Multisystem involvement -- three or more of the following:
Gastrointestinal: vomiting or diarrhea at onset of illness
Muscular: severe myalgia or creatine phosphokinase level at least twice the upper limit of normal for laboratory
Mucous membrane: vaginal, oropharyngeal, or conjunctival hyperemia
Renal: blood urea nitrogen or creatinine at least twice the upper limit of normal for laboratory or urinary sediment with pyuria (greater than or equal to 5 leukocytes per high-power field) in the absence of urinary tract infection
Hepatic: total bilirubin, serum glutamic-oxaloacetic trans-aminase (SGOT), or serum glutamic-pyruvic transaminase (SGPT) at least twice the upper limit of normal for laboratory
Hematologic: platelets <100,000/mm superscript 3
Central nervous system: disorientation or alterations in consciousness without focal neurologic signs when fever and hypotension are absent
Negative results on the following tests, if obtained:
Blood, throat, or cerebrospinal fluid cultures (blood culture may be positive for Staphylococcus aureus)
Rise in titer to Rocky Mountain spotted fever, leptospirosis, or measles
Case classification
Probable: a case with five of the six clinical findings described above
Confirmed: a case with all six of the clinical findings described above, including desquamation, unless the patient dies before desquamation could occur
An illness with the following clinical manifestations:
Fever -- temperature greater than or equal to 38.9 C (102 F)
Rash -- diffuse macular erythroderma
Desquamation -- 1-2 weeks after onset of illness, particularly palms and soles
Hypotension -- systolic blood pressure less than or equal to 90 mm Hg for adults or less than fifth percentile by age for children <16 years of age; orthostatic drop in diastolic blood pressure greater than or equal to 15 mm Hg from lying to sitting, orthostatic syncope, or orthostatic dizziness
Multisystem involvement -- three or more of the following:
Gastrointestinal: vomiting or diarrhea at onset of illness
Muscular: severe myalgia or creatine phosphokinase level at least twice the upper limit of normal for laboratory
Mucous membrane: vaginal, oropharyngeal, or conjunctival hyperemia
Renal: blood urea nitrogen or creatinine at least twice the upper limit of normal for laboratory or urinary sediment with pyuria (greater than or equal to 5 leukocytes per high-power field) in the absence of urinary tract infection
Hepatic: total bilirubin, serum glutamic-oxaloacetic trans-aminase (SGOT), or serum glutamic-pyruvic transaminase (SGPT) at least twice the upper limit of normal for laboratory
Hematologic: platelets <100,000/mm superscript 3
Central nervous system: disorientation or alterations in consciousness without focal neurologic signs when fever and hypotension are absent
Negative results on the following tests, if obtained:
Blood, throat, or cerebrospinal fluid cultures (blood culture may be positive for Staphylococcus aureus)
Rise in titer to Rocky Mountain spotted fever, leptospirosis, or measles
Case classification
Probable: a case with five of the six clinical findings described above
Confirmed: a case with all six of the clinical findings described above, including desquamation, unless the patient dies before desquamation could occur
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Dec 02, 2012