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Anaesthetic overview :

Defects of eye, nose, lip and forebrain, polydactyly, scalp lesions, cardiac and renal defects, early death

Structural: Cleft lip/palate, cardiac, renal, rib, CNS, colon anomalies, micrognathia, diaphragmatic defect (respiratory distress) Misc: Seizures, hypotonia, cerebellar hypoplasia

Radiologic evaluation for rib or vertebral anomalies; evaluate for upper airway obstruction or defects and cardiac, renal, neurologic and pulmonary function

Anesth Analg. 2000 Oct;91(4):837-55.
Specific genetic diseases at risk for sedation/anesthesia complications.
Butler MG, Hayes BG, Hathaway MM, Begleiter ML.

www.anesthesia-analgesia....

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