Patient (condition)
Aliases:
Topic aliases are alternate phrasings for a particular topic.
Truncal valve
Truncas arteriosus
A congenital anomaly caused by the failed development of TRUNCUS ARTERIOSUS into separate AORTA and PULMONARY ARTERY. It is characterized by a single arterial trunk that forms the outlet for both HEART VENTRICLES and gives rise to the systemic, pulmonary, and coronary arteries. It is always accompanied by a ventricular septal defect.
www.nlm.nih.gov/cgi/mesh/...
www.nlm.nih.gov/cgi/mesh/...
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Nov 14, 2012
Classification of truncus arteriosus is either by Collet and Edwards, or Van Praag.
Picture from Boston Children's Hospital www.childrenshospital.org...
Picture from Boston Children's Hospital www.childrenshospital.org...
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Deletion of chromosome 22q11 is present in approximately 11–35% of patients with truncus arteriosus, and this chromosomal abnormality is associated with DiGeorge syndrome and velocardio facial-syndrome.
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Nov 13, 2012
Most patients have a ventricular septal-defect, although an intact septum can occur.
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As the pulmonary vascular resistance falls, patients can develop pulmonary overcirculation manifesting as CHF with early development of pulmonary veno-occlusive-disease (PVOD).
Truncal valve regurgitation may further worsen heart failure, and coronary ischemia may be occur as a consequence of low diastolic pressures.
Alternatively, pulmonary artery stenosis may be present, limiting pulmonary blood flow.
Andropolous, Anaesthesia for Congenital Heart Disease. p440
Truncal valve regurgitation may further worsen heart failure, and coronary ischemia may be occur as a consequence of low diastolic pressures.
Alternatively, pulmonary artery stenosis may be present, limiting pulmonary blood flow.
Andropolous, Anaesthesia for Congenital Heart Disease. p440
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