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Tumor lysis syndrome occurs when tumor cells release their contents into the bloodstream, either spontaneously or in response to therapy.
Characteristic findings include hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia.
These electrolyte and metabolic disturbances can progress to clinical toxic effects, including renal insufficiency, cardiac arrhythmias, seizures, and death due to multiorgan failure.
dx.doi.org/10.1056/NEJMra...
Characteristic findings include hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia.
These electrolyte and metabolic disturbances can progress to clinical toxic effects, including renal insufficiency, cardiac arrhythmias, seizures, and death due to multiorgan failure.
dx.doi.org/10.1056/NEJMra...
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Dec 24, 2012