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Intermediate duration monoquaternary aminosteroid non-depolarising muscle relaxant. Intermediate duration is due to its high lipid solubilty, rapid hepatic uptake and biliary and renal exretion.

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Intubating dose 0.1mg/kg (7mg in 70kg pt) (ED95 0.05mg/kg)

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Clinically significant residual neuromuscular block (TOF ratio ~0.75) could be present for up to 4hrs after a single dose of vecuronium 0.1 mg/kg. refl.in/9v

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The metabolite, 3-desacetylvecuronium has 80% of the neuromuscular blocking potency of vecuronium
and will contribute to any residual blockade refl.in/a1

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