Clinical Procedure
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All recommendations on anticoagulation and regional in vascular surgery originally from Rao TL, El-etr AA. Anesthesiology 1981 55:139-146
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May 18, 2011
When administering protamine to reverse anticoagulation, do this slowly to avoid the haemodynamic consequences of rapid administration. The consequences are primarly increased pulmonary hypertension, fall in systemic vascular resistance, and decreased cardiac output.
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Apr 21, 2012