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Executive summary - "A new analysis of the 2010 CRASH-2 study shows that tranexamic acid should be given as early as possible to bleeding trauma patients; if treatment is not given until three hours or later after injury, it is less effective and could even be harmful. In this new analysis, the CRASH-2 investigators analysed subgroups of patients who had received tranexamic acid less than one hour after injury; between one and three hours after injury; or more than three hours after injury."
www.thelancet.com/crash-2
www.thelancet.com/crash-2
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Mar 20, 2014