Drug
 
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Naltrexone is a highly specific opioid antagonist with high affinity. Competitively inhibits opioid agonists (@methadone, heroin, morphine) refl.in/4n

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Cease 72hrs prior to elective surgery. refl.in/4n

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For mild pain use multimodal non-opioid analgesia. refl.in/4n

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If emergency surgery, consult drug and alcohol physician. refl.in/4n

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Similar structure to naloxone but it has a higher oral efficacy and a longer duration of action.
An oral dose reaches peak plasma concentration in 1-2 hours with a half life of approximately 14 hours

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